The Timbuk2 Q features easy access to your laptop (fits up to 15" laptops) via a padded outer flap, with a sweet durable ballistic nylon construction throughout. You also tons of pockets for accessories, power brick storage, and multiple grab handles. However, one of the most important necessities of a great bag is a comfortable shoulder strap, and we're glad to hear pop culture blog Cool Hunting as well as many other review sites have noted the straps to be very lightweight and comfortable.
You can grab the Timbuk2 Q Messenger Backpack for $100 (actually, it looks like Amazon's selling it for $90 right now). Comes in 3 colors; black, army green, and brown.